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What is Ozempic?
Both Ozempic and Wegovy are brands of Semaglutide. It is a long-acting GLP-1 receptor agonist that can be administered subcutaneously once a week.
And it is demonstrated to be effective in weight loss in clinical studies conducted on patients without type 2 diabetes. In fact, Ozempic has been developed to treat type 2 diabetes, as it helps lower blood glucose levels.
However, this is the most important option for people to have diabetes.
Keep in mind that only the injectable form, Wegovy, is approved for the treatment of obesity (not in the oral version). It has also been shown that semglutide reduces cardiovascular (CV) risk factors in patients with established CV disorders in some studies on CV outcomes.
How does Ozempic work for peso loss?
Once you are considered overweight or obese, the treatment is as follows: the injections of Ozempic at the maximum dose (2.4 mg a settimana) help to reach the maximum weight loss.
But patients should not start immediately with the maximum dose, since some non-tolerant patients may have side effects, such as nausea or vomiting. Ecco perché si recommend un aumento graduale della dose.
How semaglutide (Ozempic and Wegovy) works for losing weight is quite interesting. GLP-1 is an important incretin hormone in humans. In other words, it increases the insulin section, inhibits the release of glucagon and suppresses hepatic gluconeogenesis.
Semaglutide also causes delayed gastric emptying, a reduction in appetite and energy intake, which is why it has beneficial effects on weight loss. It reduces the speed with which the stomach empties the food after a meal (svuotamento gastrico). The longer the gastric emptying takes place, the longer the food remains in the stomach, making you feel satisfied longer.
This translates into a reduction of fame and appetite. In general, i pazienti che assumono Ozempic o Wegovy finiscono per mangiare meno cibo e quindi curtaine peso.
Ozempic not only affects gastric emptying, it also affects the GLP-1 receptors present in the hypothalamus, responsible for the regulation of food intake in the nervous system. To reduce the sensationa di fame e appetito in obese individuals.
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In addition, GLP-1 also acts on the receptors responsible for satiety in the brain. Stimulates these specific neurons, increasing satiety in patients who have received Ozempic. Ora che sai a cosa serve Ozempic, let's take a closer look at the dosage and ad altre istruzioni per l'assunzione.
Where do I inject Ozempic?
A study has demonstrated that taking Ozempic a digiuno has the most optimal effect for reaching the therapeutic concentration. Fasting is beneficial for another half hour after taking the dose.
Furthermore, Ozempic must be administered sotto la pelle, in the subcutaneous or adipose layer, in the lower part of the abdomen (near the waist), in the anterior part of the thighs or in the upper part of the arm. Non iniettare Ozempic in a muscle or in a vein.
Be sure to rotate (change) the injection site for each injection. Don't use the same injection site for each injection, choose the same site, don't use the same position every time.
With Ozempic è necessaria la titolazione della dose. That is to say, patients should start the therapy with 0.25 mg, then increase it to 0.5 mg and then to 1 mg, maintaining an interval of 4 weeks. The Ozempic pen (red and blue) is available in a concentration of 1.34 mg/ml.
La penna rossa delivers an initial dose of 0.25 mg and 0.5 mg per scope of maintenance. On the other hand, la penna blu è pensata per 1.0 mg (dose massima di mantenimento) of Semaglutide.
What foods should you avoid while taking Ozempic?
Quando i pazienti niziano ad assumere Ozempic, possono verifarsi alcuni effetti collaterali come diarrhoea, nausea o vomito. Ma questi possono compirire nel tempo mano che il patient si abitu al pharmaco.
Per aiutare il corpo adadatarsi al pharmaco e al dosaggio, si raccomanda di avoid cibi fritti e cibi fatsi, come il fast food e cibi ricchi di zucchero. Ozempic e cibi fatsi non sono amici: possono escacerbere gli effetti collaterali.
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